Mittwoch, 14. November 2012

Study Stem cells from strangers tin fix hearts

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In this Wednesday, Oct. 31, 2012..

LOS ANGELES (AP) Researchers are reporting a opener advance among using stem cells to nail hearts damaged onward center attacks. In a study stem cells donated along strangers proved as secure and efficacious as patients' own cells as helping restore megalopolis tissue.

The work involved equitable 30 patients among Miami and Baltimore,merely it proves the concept that anyone's cells can be adapt apt treat such cases. Doctors are excited for this suggests that stem cells could be banked for off-the-shelf use after hub attacks,just as blood is kept aboard hand immediately.

Results were discussed Monday at an American Heart Association conference within California and published amid the Journal of the American Medical Association.

The learn accustom a specific type of stem cells from bone marrow that researchers believed would never be rejected by recipients. Unlike additional cells, these paucity a opener feature on their surface that makes the immune system perceive them as alien tissue and invasion them, explained the study's leader Dr. Joshua Hare of the University of Miami.

The patients amid the learn had suffered hub attacks years earlier, some order of the day 30 years antecedent All had developed heart failure because the scar tissue from the center invasion had weakened their hearts so much that they grew tremendous and flabby, unable apt pump blood mainly.

Researchers advertised as people apt furnish marrow which namely removed using a pin into a hip bone. The cells were taken from the essence and amplified for nearly a month surrounded a lab at Baltimore's Johns Hopkins University,next returned to Miami apt be adapt for treatment, which did never involve surgery.

The cells were delivered amongst a tube pushed amongst a groin aisle into the center approximate the scarred zone Fifteen patients were given cells from their own core and 15 others, cells from strangers.

About a annual behind scar tissue had been reduced onward almost one-third. Both groups had improvements amid how distant they could hike and amid quality of life. There was not significant feud among one measure of how well their hearts were able apt pump blood,yet doctors wish these patients will continue to edit over period,or that refinements among treatment ambition guide to better results.

The big attraction namely being able apt use cells supplied onward others, with no blood or tissue matching needed.

"You could have the cells prepared to go among the blood bank so while the patient comes in for a therapy there's not delay Hare said. "It's likewise cheaper apt tell the donor cells," and a single elite donor can furnish enough cells apt treat as much as 10 people.

Dr. Elliott Antman of Harvard-affiliated Brigham and Women's Hospital among Boston who heads the center conference, praised the go.

"That opens up an entire current street for stem cell treatment,favor a sophisticated version of a blood bank," he said. There's an advantage surrounded never having apt establish a compartment treatment as every patient, and it could remainder them the pain and wait of having their own marrow harvested, he said.

The study was sponsored onward the National Institutes of Health. Hare owns stock in a biotech company working on a treatment using a blend of cells.

Juan Lopez received his own cells surrounded the study and said it improved his symptoms so much that by age 70, he was able apt return to his job as an engineer and sales manager for a roofing manufacturer and ride an penalty bicycle.

"It has been a life-changing experience," said Lopez, who lives surrounded Miami. "I can feel day according daytime week forward week, month along month, my improvement. I don't have any shortness of expiration and my energy class namely access up there. I don't have any liquid among my lungs."

And, he said happily, "My sex drive has improved!"

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Marilynn Marchione can be followed by ssociation: ssn.org
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